A Nanobiocatalyst‐Driven Hybrid System for Efficient and Sustainable Hydrogen Production via Electron Flow Optimization
Abstract
Abstract Biohydrogen production offers a promising pathway for developing clean and renewable energy sources. However, its practical application has been hindered by low efficiency and sustainability issues. Here, it is introduced an energy‐efficient and output‐sustainable hybrid system (LPBC/CH system) for biohydrogen production by integrating self‐assembling intermetallic ( L 1 0 ) FePt@polypyrrole nanobiocatalysts (LPBC) with Clostridium pasteurianum . The engineered LPBC, characterized by optimal atomic structures and defined electronic properties, demonstrates robust transcriptional enhancement efficiency and biocatalytic capability, leading to an ≈103% increase in hydrogen production rate and a 57% enhancement in hydrogen yield to the bare C. pasteurianum system. Within the LPBC/CH system, the nanobiocatalysts target NADH and [FeFe] hydrogenase, triggering efficient tandem biocatalytic reactions for proton reduction. Notably, the LPBC achieves sustained performance for at least 30 days – a benchmark unmatched by other reported nanobiocatalysts. This study not only advances the frontiers of biohydrogen production but also establishes a universal framework for constructing hybrid systems with superior efficiency and sustainability.
Article Details
Authors (17)
Linlin Yang
Institute of Molecular Medicine and Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine, Renji Hospital, School of Medicine
Yizhe Dong
School of Pharmacy National Key Laboratory of New Pharmaceutical Preparations and Excipients Key Laboratory of Innovative Drug Development and Evaluation Hebei Medical University Shijiazhuang P.R. China
Dong Zhao
Xiangyu Li
Jiajie He
1National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University,Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Department of Hematology, Suzhou, China
Tin Pou Lai
State Key Laboratory of Medicinal Chemical Biology College of Life Science Nankai University Tianjin 300350 P. R. China
Enze Zhou
Toshiyuki Ueki
Electrobiomaterials Institute Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education) Northeastern University Shenyang 110819 P. R. China
Yixing Li
Xiangying Meng
College of Sciences, Northeastern University 1 , Shenyang 110819,
Liyun Zhang
School of Chemistry and Chemical Engineering, Chongqing University, 174 Shazheng Street, Chongqing 400030, P. R. China
Bin Yu
Wenli Pei
Electrobiomaterials Institute Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education) Northeastern University Shenyang 110819 P. R. China
Yongqiang Fan
Electrobiomaterials Institute Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education) Northeastern University Shenyang P.R. China
Tingyue Gu
Department of Biological Sciences and Molecular & Cellular Biology Program Ohio University Athens OH USA
Fuhui Wang
State Key Laboratory of Digital Steel, School of Materials Science and Engineering
Dake Xu
State Key Laboratory of Digital Steel, School of Materials Science and Engineering