Ethics of Backfilling in Early-Phase Oncology Trials

Marieke J. Hollestelle; Rob Kessels; Peter M. van de Ven; Rieke van der Graaf

doi:10.1200/jco-25-02005

Ethics of Backfilling in Early-Phase Oncology Trials

M Marieke J. Hollestelle (Julius Center for Health Sciences and Primary Care, Department of Global Public Health and Bioethics, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands) R Rob Kessels (Julius Center for Health Sciences and Primary Care, Department of Data Science and Biostatistics, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands) P Peter M. van de Ven (Julius Center for Health Sciences and Primary Care, Department of Data Science and Biostatistics, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands) R Rieke van der Graaf (Julius Center for Health Sciences and Primary Care, Department of Global Public Health and Bioethics, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands)

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Article Details

Journal Journal of Clinical Oncology

Volume / Issue Vol. 44, Issue 8

Published March 10, 2026

Pages 626-629

DOI 10.1200/jco-25-02005

ISSN 0732-183X

Publisher Lippincott Williams & Wilkins

Journal Info

Journal of Clinical Oncology

Lippincott Williams & Wilkins

ISSN: 0732-183X Health Sciences

Authors (4)

M

Marieke J. Hollestelle

Julius Center for Health Sciences and Primary Care, Department of Global Public Health and Bioethics, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands

R

Rob Kessels

Julius Center for Health Sciences and Primary Care, Department of Data Science and Biostatistics, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands

P

Peter M. van de Ven

Julius Center for Health Sciences and Primary Care, Department of Data Science and Biostatistics, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands

R

Rieke van der Graaf

Julius Center for Health Sciences and Primary Care, Department of Global Public Health and Bioethics, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands

Ethics of Backfilling in Early-Phase Oncology Trials

Article Details

Journal Info

Authors (4)

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