Materials Advances in Devices for Heart Disease Interventions

G Gagan K. Jalandhra (Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia) L Lauryn Srethbhakdi (Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia) J James Davies C Chi Cong Nguyen P Phuoc Thien Phan Z Zachary Och (Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia) A Aditya Ashok (Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia) K Khoon S. Lim (School of Medical Sciences University of Sydney Sydney Australia) H Hoang‐Phuong Phan (School of Mechanical and Manufacturing Engineering University of New South Wales Sydney NSW 2052 Australia) T Thanh Nho Do N Nigel H. Lovell J Jelena Rnjak‐Kovacina (Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia)

Abstract

Abstract Heart disease encompasses a range of conditions that affect the heart, including coronary artery disease, arrhythmias, congenital heart defects, heart valve disease, and conditions that affect the heart muscle. Intervention strategies can be categorized according to when they are administered and include: 1) Monitoring cardiac function using sensor technology to inform diagnosis and treatment, 2) Managing symptoms by restoring cardiac output, electrophysiology, and hemodynamics, and often serving as bridge‐to‐recovery or bridge‐to‐transplantation strategies, and 3) Repairing damaged tissue, including myocardium and heart valves, when management strategies are insufficient. Each intervention approach and technology require specific material properties to function optimally, relying on materials that support their action and interface with the body, with new technologies increasingly depending on advances in materials science and engineering. This review explores material properties and requirements driving innovation in advanced intervention strategies for heart disease and highlights key examples of recent progress in the field driven by advances in materials research.

Article Details

Volume / Issue Vol. 37, Issue 27
Published July 01, 2025
ISSN 0935-9648
Publisher Unknown Publisher

Journal Info

Advanced Materials

Unknown Publisher

ISSN: 0935-9648 Physical Sciences

Authors (12)

G

Gagan K. Jalandhra

Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia

L

Lauryn Srethbhakdi

Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia

J

James Davies

C

Chi Cong Nguyen

P

Phuoc Thien Phan

Z

Zachary Och

Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia

A

Aditya Ashok

Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia

K

Khoon S. Lim

School of Medical Sciences University of Sydney Sydney Australia

H

Hoang‐Phuong Phan

School of Mechanical and Manufacturing Engineering University of New South Wales Sydney NSW 2052 Australia

T

Thanh Nho Do

N

Nigel H. Lovell

J

Jelena Rnjak‐Kovacina

Graduate School of Biomedical Engineering University of New South Wales Sydney NSW 2052 Australia