Use of Low-Value Cancer Treatments in Medicare Advantage Versus Traditional Medicare

J Jeah Jung (Department of Health Administration and Policy, College of Public Health, George Mason University, Fairfax, VA) C Caroline Carlin (Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN) R Roger Feldman (Division of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis, MN) G Ge Song A Aaron Mitchell (Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY)

Abstract

PURPOSE Medicare Advantage (MA) provides beneficiaries an option to receive Medicare benefits from private plans. Although MA covers over half of the Medicare population, limited information exists about how utilization of cancer treatments in MA differs from traditional Medicare (TM). We compared use of low-value cancer treatments between MA and TM and analyzed variation in use of low-value cancer treatments across large MA insurers. METHODS Using national Medicare data, we performed retrospective analyses of beneficiaries who had a new cancer diagnosis between 2016 and 2021 and who were at risk of receiving a low-value treatment: granulocyte-colony stimulating factors (GCSFs) for patients receiving low-risk chemotherapy, denosumab for castration-sensitive prostate cancer (CSPC), nab-paclitaxel instead of paclitaxel for breast or lung cancers, adding bevacizumab to carboplatin plus paclitaxel for ovarian cancer, and branded drugs or biologics for which generic or biosimilar versions existed. RESULTS Use of any low-value cancer treatment was 1.7 percentage points lower in MA than in TM (34.2% v 35.9%; P < .001). MA had lower utilization rates than TM for GCSF among patients receiving low-risk chemotherapy (7.3% v 8.9%; P < .001), denosumab for CSPC (26.4% v 33.1%; P < .001), nab-paclitaxel for breast or lung cancer (7.9% v 8.7%; P < .001), addition of bevacizumab for ovarian cancer (8.3% v 10.5%; P < .001), and biologics with biosimilar alternatives (66.8% v 68.5%; P < .001). Use of branded drugs did not significantly differ between MA and TM. The differences in use of low-value cancer treatments from TM varied moderately across large MA insurers. CONCLUSION MA has lower use of low-value cancer treatments than TM, with varying degrees across large MA insurers. Efforts are needed to identify effective strategies to reduce use of low-value cancer treatments.

Article Details

Volume / Issue Vol. 43, Issue 20
Published July 10, 2025
Pages 2245-2254
ISSN 0732-183X
Publisher Lippincott Williams & Wilkins

Journal Info

Journal of Clinical Oncology

Lippincott Williams & Wilkins

ISSN: 0732-183X Health Sciences

Authors (5)

J

Jeah Jung

Department of Health Administration and Policy, College of Public Health, George Mason University, Fairfax, VA

C

Caroline Carlin

Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN

R

Roger Feldman

Division of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis, MN

G

Ge Song

A

Aaron Mitchell

Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY