Journal of Clinical Oncology
Articles in this Issue
Anitocabtagene autoleucel (anito-cel) clinical trial manufacturing experience in patients with relapsed/refractory (RR) or newly diagnosed (ND) multiple myeloma (MM).
2550 Background: Anito-cel is an autologous D-Domain–based anti-BCMA chimeric antigen receptor (CAR) T-cell therapy that d...
Impact of niraparib maintenance on progression-free survival and overall survival: An updated meta-analysis.
5591 Background: Niraparib is an oral poly(ADP-ribose) polymerase (PARP) inhibitor used as maintenance therapy in advanced...
LIF expression as a predictive biomarker in metastatic renal cell carcinoma.
4548 Background: Clear cell renal cell carcinoma (ccRCC) is biologically heterogeneous, and optimal selection between VEGF...
FF-10832 liposomal gemcitabine monotherapy or combination with pembrolizumab in patients with advanced non–small cell lung cancer.
8560 Background: FF-10832, a stable liposomal formulation of gemcitabine with a prolonged half-life (mean t...
Multidisciplinary AE management education for EGFR-mutated NSCLC: Mixed-methods QI outcomes.
e23368 Background: Anti-EGFR therapies for EGFR-mutated NSCLC have dermatologic and other adverse events (AEs) that benefi...
Effects of immune checkpoint inhibitor on the quality of life of patients with advanced/metastatic esophageal, gastro-esophageal junction, and gastric cancers: A systematic review of randomized controlled trials.
e16351 Background: Immune checkpoint inhibitors (ICIs) have demonstrated survival benefits in patients with advanced or me...
Phase 1b dose-expansion study of IMC-002, a anti-CD47 monoclonal antibody, in patients with advanced triple negative breast cancer (TNBC).
2524 Background: IMC-002 is a novel therapeutic agent with a distinct mechanism of action. In a phase 1a dose-escalation s...
GDF-15 in oropharyngeal squamous cell carcinoma (OPSCC): Association of an HPV-dependent biomarker with malnutrition and low skeletal muscle.
6110 Background: GDF15 is a stress-response cytokine implicated in systemic inflammation and cancer-related wasting. We as...
Impact of SGLT2 inhibitors on clinical outcomes in diabetic patients with CLL receiving BTK inhibitors: A global propensity-matched study.
7051 Background: Diabetic patients with chronic lymphocytic leukemia (CLL) receiving Bruton’s tyrosine kinase inhibitors (...
Prospective analysis of cardiovascular complications in HER2-positive breast cancer patients treated with anthracycline-free regimens.
e12545 Background: The assessment of cardiovascular complications (CVC) frequency and the predictive role of the HFA-ICOS...
ILCness to stratify lobular-like breast cancer biology and as an outcome independent of <i>CDH1</i> mutation in early ER-positive/HER2-negative breast cancer.
576 Background: Invasive lobular carcinoma (ILC) represents a distinct histological subtype of breast cancer; however, its...
Real-world utilization and outcomes of hematopoietic stem cell transplantation in testicular cancer.
e17016 Background: Approximately 10–30% of patients with testicular cancer experience relapse or develop platinum-refracto...
Survival outcomes with contemporary treatments including immunotherapy for poorly differentiated neuroendocrine carcinomas of the head and neck.
6115 Background: Poorly differentiated Neuroendocrine Carcinomas of the Head and Neck (HN-NECs) are rare aggressive malign...
Mortality from pulmonary embolism among patients with lung and bronchus malignancies: National trends and forecasting from CDC WONDER (1999–2030).
e20116 Background: Pulmonary embolism (PE) represents a major cause of preventable mortality in patients with lung cancer...
Attenuation of long-term survival benefit of biological therapy in metastatic colorectal cancer (mCRC): Real-world data validation and molecular characterization.
e15589 Background: Incorporation of biologic drugs to chemo has improved overall survival (OS) of patients with metastatic...
Can robotic surgery better preserve sensory function?: The significance and strategy of nerve preservation in axillary lymph node dissection.
582 Background: Conventional axillary lymph node dissection (C-ALND) carries a high risk of damaging the intercostobrachia...
Driving efficiency in oncology care: Tactical solutions for inpatient flow challenges.
e13566 Background: Hospital compression limits access to timely care with a negative impact on patients. These pressures h...
Neoadjuvant camrelizumab with chemotherapy (NACI) in PD-L1-negative locally advanced cervical cancer: An open-label, multi-center, single-arm, phase 2 trial.
e17510 Background: Locally advanced cervical cancer (LACC) remains associated with suboptimal outcomes with conventional t...
Clinically actionable TURBT-derived bladder cancer organoid pharmacotyping as a predictor of postoperative outcomes in a prospective multicenter study.
e16613 Background: Post-TURBT chemotherapy is largely empiric despite marked inter-patient heterogeneity in bladder cancer...
Clinical outcomes of muscle-invasive and metastatic, bladder, and urethral pure adenocarcinoma (BUAdenoCa): An international study from the Global Society of Rare Genitourinary Tumors (GSRGT).
e16565 Background: BUAdenoCa are rare and their management options are limited. The GSRGT assembled an international cohor...
Does surgery improve breast cancer–specific survival in low-grade DCIS?: A 20-year population-based analysis by nuclear grade.
578 Background: Active surveillance is increasingly discussed for low-risk ductal carcinoma in situ (DCIS), yet randomized...
Baseline CT-derived QVT score as predictor of bevacizumab benefit in advanced non-squamous NSCLC: A retrospective biomarker analysis of SWOG S0819.
8549 Background: Despite two decades of anti-angiogenic therapy in NSCLC, no predictive biomarker identifies which patient...
Osimertinib combined with bevacizumab and chemotherapy as 1L treatment in EGFR-mutated metastatic non-squamous non-small cell lung cancer (nsq NSCLC) with concurrent mutations.
8625 Background: Concurrent mutations in EGFR sensitive mutations (19 del/21 L858R) are associated with poor prognosis. Pr...
Epidemiological trends and burden of pancreatic cancer in the United States: A retrospective analysis from 1990 to 2023 with advanced machine learning forecasting to 2050.
e16402 Background: Pancreatic cancer remains a leading cause of cancer-related burden in the United States, with persisten...
Clinical impact of R0 resection after chemotherapy in initially unresectable metastatic colorectal cancer: A pooled analysis of the ARCAD database.
e15557 Background: In metastatic colorectal cancer (mCRC), systemic chemotherapy can enable conversion surgery in a subset...