Journal of Clinical Oncology
Articles in this Issue
Multicentre trial of telemonitored circadian rhythms and electronic patient-reported outcomes (ePROs) for improving tolerability of initial mFOLFIRINOX cycles in patients (pts) with advanced pancreatic ductal adenocarcinoma (PDAC): MultiDom (NCT04263948).
4204 Background: Severe Adverse Events (SAEs) requiring emergency admissions (EAs) alter quality of life and treatment eff...
Immunologic and clinical outcomes of perfluoroalkyl substances (PFAS) exposure in solid tumors treated with pembrolizumab.
2539 Background: Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are two major PFAS with persistent and...
Circulating cadherin-17 (CA17) in blood as a diagnostic biomarker for gastric cancer.
10569 Background: The asymptomatic onset of gastric cancer (GC) frequently leads to delayed diagnosis resulting in poor su...
Lucicebtide (ST101) plus chemoradiation in newly diagnosed GBM patients: Efficacy, pharmacodynamics, and safety from phase 2 window-of-opportunity study.
2079 Background: Glioblastoma (GBM) is a lethal brain malignancy with no cure. Recurrent GBM (rGBM) is enriched in a mesen...
Safety and efficacy of BAT8006 in combination with BAT1308 in patients with advanced endometrial cancer.
5512 Background: BAT8006 is a folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), while BAT1308 is a recombin...
Early versus delayed inpatient radiotherapy in head and neck cancer and associated in-hospital outcomes.
e18088 Background: Early initiation of radiotherapy (RT) in head and neck cancer (HNC) may improve outcomes by enhancing t...
Patterns, resource impact, and disparities in low value care during terminal hospitalizations for lung cancer: A national analysis (2016-2019).
e23228 Background: High-intensity interventions near the end of life, including invasive mechanical ventilation (IMV) and...
PONV risk score and gender as predictors of delayed ambulation in outpatient thyroid and parathyroid surgery.
e18087 Background: Enhanced Recovery After Surgery (ERAS) protocols aim to improve perioperative outcomes by promoting ear...
A multicenter phase 1/1b study of AMG 436 as monotherapy and combination therapy in patients with advanced MSI-H/dMMR solid tumors.
TPS3173 Background: Microsatellite instability-high (MSI-H)/mismatch repair deficiency (dMMR) tumors are characterized by...
Audiometric outcomes for intravenous sodium thiosulfate for cisplatin-induced ototoxicity prevention in adults with head and neck cancer.
e18110 Background: Cisplatin-induced ototoxicity (CIO) is a well-known complication of platinum-based chemotherapy that ca...
StrateGIST 3: A randomized, phase 3 study of velzatinib (IDRX-42) versus sunitinib in patients with advanced gastrointestinal stromal tumors after imatinib therapy.
TPS11588 Background: Most gastrointestinal stromal tumors (GISTs) are driven by mutations in KIT...
Pilot RCT of a patient-centered communication intervention to promote values-based treatment decision-making in older adults with AML.
12092 Background: Older adults with acute myeloid leukemia (AML) often have limited involvement in high-stakes treatment d...
Prediction of postoperative recurrence in non–small cell lung cancer using machine learning approaches.
e20020 Background: Early-stage NSCLC can have favorable survival outcomes; however, postoperative recurrence remains commo...
Phase 1, multicenter, open-label study of HSK46575 in patients with metastatic castration-resistant prostate cancer progressing after next-generation hormonal agents and chemotherapy.
5047 Background: The development and progression of prostate cancer are regulated by steroid hormones. HSK46575 Tablet is...
Diagnostic accuracy of Color Doppler ultrasound for detecting portal venous thrombosis in hepatocellular carcinoma patients: A meta-analysis.
e16158 Background: Portal venous thrombosis (PVT) is a frequent and clinically significant complication in patients with h...
Non-blood liquid biopsy in nipple discharge for decoding tumor-derived CNV signatures for breast cancer detection and prognostication.
e12578 Background: Nipple discharge is a prevalent symptom affecting about 80% of women during reproductive years, yet onl...
PROgress Tracker Breast Cancer Registry: Reporting worry of illness from a longitudinal peer-led, national patient-reported outcomes (PRO) registry.
11112 Background: PROgress Tracker Breast Cancer Registry is a national, ethics approved non-interventional patient-report...
Phase 1/2 study of the novel Werner helicase inhibitor EIK1005 as monotherapy and in combination with pembrolizumab in patients with advanced solid tumors, including MSI-H or dMMR tumors.
TPS3170 Background: Cancers with deficient mismatch repair (dMMR) have high microsatellite instability (MSI-H) and are rep...
The effects of Mediterranean diet, physical activity, and vitamin D on breast cancer recurrence and cardiometabolic health: A multicenter randomized trial.
511 Background: Low quality diets and physical inactivity are two modifiable lifestyle factors that together with vitamin...
Efficacy of velzatinib (IDRX-42) in patients with advanced/metastatic GIST by line of therapy and circulating tumor DNA response in the phase 1/1b StrateGIST 1 trial.
11520 Background: Most gastrointestinal stromal tumors (GIST) are driven by mutations in KIT...
Oncologic safety of autologous fat grafting as part of local–regional management of breast cancer.
e12623 Background: Autologous fat grafting (AFG) is increasingly incorporated into breast reconstruction after mastectomy...
Trends and disparities in cervical cancer and heart failure mortality: A 21-year retrospective study of the US population using the CDC database.
e17524 Background: Cervical cancer remains one of the leading causes of female cancer mortality, while heart failure drive...
Prognostic associations of the G8 geriatric screening tool in the EORTC Brain Tumor Group trials 1608 and 1709 in patients with newly diagnosed glioblastoma.
e13777 Background: The G8 screening assessment tool has been validated to assess frailty in older patients with cancer. A...
Comparison of different induction chemotherapy regimens in pediatric and adolescent patients with locally advanced nasopharyngeal carcinoma.
e18062 Background: Induction chemotherapy (IC) is a first-line treatment for locally advanced nasopharyngeal carcinoma (LA...
Utility of deep learning–derived PSMA PET biomarkers for metastatic prostate cancer.
e17002 Background: PSMA PET is increasingly used in staging and management of metastatic prostate cancer. Although qualita...