Journal of Clinical Oncology
Articles in this Issue
Substance use disorders following cancer diagnosis in adolescents and young adults: A Canadian population-based study.
e23102 Background: Substance use disorders (SUDs) can adversely affect cancer treatment and survivorship outcomes, includi...
Beyond geography: The intersecting impact of rurality, race, and depression on breast cancer survival.
11137 Background: Rural–urban disparities in breast cancer outcomes are well-documented, with rural populations typically...
National mortality trends of malignant melanoma associated with cerebrovascular diseases in the United States (1999-2023).
e21518 Background: Malignant melanoma and cerebrovascular diseases (CVDs) pose major U.S. public health burdens, with mela...
Optimal timing of circulating tumor DNA (ctDNA) dynamics to prognosticate immune checkpoint inhibitors (ICI) efficacy in patients with advanced stage melanoma.
9534 Background: ctDNA predicts relapse in resected tumors, but its role in advanced disease is less defined. We previousl...
Prognostic biomarkers in retroperitoneal dedifferentiated liposarcoma and their clinical impact on patient management.
11546 Background: The prognosis of patients (pts) with retroperitoneal dedifferentiated liposarcoma (DDLPS) is mainly driv...
Family cancer history and perceived value of multi-cancer early detection tests in a national U.S. sample.
10519 Background: Family history of cancer has a strong influence on individuals’ perceived cancer risk and has been shown...
Genotype–anatomic correlates and survival outcomes in a molecularly validated 90-patient cohort of skeletal and extraskeletal Ewing sarcomas and mimics.
e23501 Background: Ewing sarcoma (ES)—defined by FET::ETS rearrangements—and Ewing-like small round-cell mimics represent...
Trends in gastric cancer-related mortality across world bank income groups, 1980–2023: A retrospective analysis.
e16043 Background: Gastric cancer is a major global health concern and a leading cause of cancer-related mortality worldwi...
Adjuvant donafenib plus anti–PD-1 therapy in hepatocellular carcinoma with high-risk features after curative resection: A real-world study.
e16254 Background: Patients with hepatocellular carcinoma (HCC) and high-risk pathological features have a substantial ris...
Trends and factors associated with glucagon-like peptide 1 receptor agonists prescription for cancer populations with type 2 diabetes.
11181 Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are increasingly used in cancer survivors with Type...
A phase 1/2 study of mRNA-2808 in participants with relapsed or refractory multiple myeloma.
TPS7580 Background: Multiple myeloma (MM) remains mostly incurable despite therapeutic advances and relapsed or refractory...
Treatment patterns and outcomes in pacritinib-treated patients with MF and higher platelet count: MY-PAC study.
6575 Background: Pacritinib (PAC), a JAK1-sparing JAK2/IRAK1/ACVR1 inhibitor has shown spleen volume and symptom improveme...
Real-world outcomes among Medicare beneficiaries treated with first-line (1L) Bruton tyrosine kinase inhibitors (BTKis) for chronic lymphocytic leukemia (CLL).
7047 Background: Covalent BTKi monotherapies are standard of care for 1L CLL in the US. However, there is a lack of head-t...
GLP-1 receptor agonist utilization and survival outcomes in a large U.S. community oncology cohort.
11017 Background: GLP1 use has increased with 12.4% of U.S. adults reported using these treatments, driven in part by the...
Large cell carcinoma with rhabdoid phenotype: Demographics, treatment, and survival in the NCDB.
e20078 Background: Large cell carcinoma with rhabdoid phenotype (LCC-RP) constitutes <1% of lung malignancies and is as...
Phase 2 trial of lisocabtagene maraleucel for minimal residual disease in patients with large B-cell lymphoma.
TPS7107 Background: Patients with relapsed/refractory large B-cell lymphoma (LBCL) have a poor prognosis. Identifying pati...
Impact of rurality on screening and prevention strategies for patients with hereditary breast and ovarian cancer syndrome.
e22662 Background: Patients with hereditary breast and ovarian cancer syndrome (HBOC) with a germline pathogenic variant i...
Mapping the treatment journey following antibody-drug conjugate (ADC) initiation: Sequencing patterns and real world overall survival (rwOS) in non-breast solid tumors in a US community setting.
e23362 Background: With the clinical application of ADCs in solid tumors, there is a need to understand treatment sequenci...
Interim results from a prospective phase II study of stratified treatment of localized cervical esophageal squamous cell carcinoma by induction immunochemotherapy (SCENIC trial).
4086 Background: Definitive concurrent chemoradiotherapy (dCRT) is the standard treatment for cervical esophageal squamous...
Clinical outcomes and safety profile of dendritic cell–based vaccination in melanoma: Meta-analysis of reconstructed time to event data.
e14597 Background: Dendritic cell (DC) vaccination has been investigated as adjuvant immunotherapy for melanoma; however,...
Reducing stress and improving quality of life for adult breast cancer patients.
e23428 Background: Ellie Fund provides essential non-medical support services to ease daily life stressors for individuals...
Neighborhood social vulnerability and chemotherapy response in breast cancer patients.
e23083 Background: Sociodemographic disparities are a well-known influence on oncologic outcomes, however their relationsh...
Comparative effectiveness of doublet versus triplet therapy in high-volume metastatic hormone-sensitive prostate cancer: A real-world evidence study.
e17084 Background: Although the combination of androgen deprivation therapy (ADT) with an androgen receptor pathway inhibi...
National trends in non-Hodgkin lymphoma incidence in the CAR-T era: A population-based analysis using SEER Explorer data.
e19062 Background: Non-Hodgkin lymphoma (NHL) is a common hematologic malignancy in the United States. Chimeric antigen re...
Predictors of progression, survival, and psychosocial burden in early-stage breast cancer: A real-world cohort study.
e12761 Background: While early-stage breast cancer is associated with high survival rates, recurrence risk and long-term p...