Journal of Clinical Oncology
Articles in this Issue
Association of <i>Streptococcus anginosus</i> with gastric cancer progression via 2-picolinic acid.
e16136 Background: Gastric cancer (GC) is one of the most common cancers and a leading cause of cancer mortality. A divers...
Financial toxicity and quality of life in advanced lung cancer: The role of depressive symptoms.
e24110 Background: Financial toxicity (FT) is a critical burden in individuals with advanced lung cancer and is strongly a...
Patient correlates of patient-provider communication and financial toxicity in Black and White patients with cancer.
e13730 Background: Financial toxicity, the burden of treatment cost, affects up to half of people with cancer and can affe...
Clinical outcomes of ethnically and racially diverse patients with gynecologic malignancies in phase I clinical trials at a single institution (2021–2024).
e17544 Background: Phase I clinical trials offer a treatment for patients with gynecologic malignancies that have progress...
Integrated metabolite–network modeling of metabolic nodes and oncogenic signaling in gastrointestinal cancers.
e15506 Background: Gastrointestinal (GI) cancers are driven by metabolic–signaling feedback loops that stabilize tumorigen...
Efficacy and safety of tislelizumab combined with chemoradiotherapy in high-risk locoregionally advanced nasopharyngeal carcinoma.
e18071 Background: The poor prognosis of high-risk locoregionally advanced nasopharyngeal carcinoma (LANPC) due to the hig...
Echo cancer advisor: A modular AI framework for interpretable, patient-specific oncology decision support.
7522 Background: Oncology increasingly relies on large, heterogeneous datasets spanning genomics, clinical records, imagin...
Erythrocyte–anti–PD-1 conjugates in patients with advanced solid tumors resistant to anti–PD-1/PD-L1 therapy: Long-term follow-up of a phase I trial.
2553 Background: Despite the clinical success of immune checkpoint blockade, most patients with advanced solid tumors fail...
Sequencing of fallopian tube p53 signature found concurrently with p53 mutant uterine cancers and their somatic mutation profiles.
5610 Background: The tumor protein 53 gene (p53) encodes a protein that suppresses replication of DNA-damaged cells. Mutat...
Comparative efficacy and safety of first-line combination therapies with third-generation EGFR-TKIs in advanced <i>EGFR</i> -mutant NSCLC: A systematic review and network meta-analysis.
e20745 Background: While third-generation EGFR tyrosine kinase inhibitors (TKIs) are the standard first-line therapy for a...
Understanding patient priorities for survivorship care in older adults with cancer: A collaborative study by the Young Interest Group of the International Society of Geriatric Oncology.
e13789 Background: Integrating patient priorities into survivorship care for older adults with cancer is increasingly reco...
Toxicity versus benefit: A prospective matched analysis of SBRT with vs without ADT.
e17115 Background: The survival benefit of adding androgen deprivation therapy (ADT) to radiotherapy for intermediate- and...
PSG copy number amplification and association with poor survival in early-stage female lung adenocarcinoma patients.
8028 Background: Pregnancy-specific glycoproteins (PSGs) are essential for maintaining maternal immune tolerance by modula...
Factors associated with adjuvant chemotherapy initiation delays among breast cancer patients in a metropolitan healthcare system.
e12541 Background: Adjuvant chemotherapy initiation (ACI) delays in breast cancer patients are a critical concern, as they...
Cardiotoxicity and efficacy outcomes of SPEDOX-6 for targeted treatment of soft tissue sarcomas.
e23534 Background: Soft tissue sarcomas (STSs) are extremely aggressive & deadly rare tumors with multiple subtypes. E...
Barriers and facilitators of advance care planning in cancer patients in southeast Alabama: An observational study.
e24039 Background: Advance Care Planning (ACP) plays a crucial role in ensuring that patients facing serious illness, such...
Patient-reported impact of a digital breast cancer survivorship community in Saudi Arabia.
e13788 Background: Breast cancer survivors in conservative societies often face cultural, social, and logistical barriers...
Clinical outcomes of [ <sup>177</sup> Lu]Lu-DOTA-TATE ( <sup>177</sup> Lu-DOTATATE) vs everolimus (EVE) in managing patients (pts) with gastroenteropancreatic-neuroendocrine tumors (GEP-NETs): Real-world analysis of the PRIME initiative.
e16316 Background: GEP-NETs arise from neuroendocrine cells of the digestive tract (88%) or pancreas (12%). Therapies for...
Sequence of similar-payload ADCs: Does it make sense in real-world HER2-low advanced breast cancer?—The Portuguese national study.
1140 Background: New-generation Antibody-Drug Conjugates (ADC) have expanded treatment options for HER2-low advanced breas...
AI–assisted survival prediction in glioma: Meta-analysis of prospective and controlled studies.
e14000 Background: Accurate survival prediction in glioma is critical for individualized treatment planning, progn...
Mediterranean CD19 genetic variations and potential influence on CAR T-cell therapy efficacy: Implications for population-tailored immunotherapy.
7008 Background: CAR T-cell therapy has transformed the treatment of B-cell malignancies. However, relapse due to CD19 ant...
To rechallenge or not to rechallenge? Immune-checkpoint inhibitor–associated neurotoxicity in advanced melanoma patients.
e24187 Background: Immune checkpoint inhibitors (ICIs) are a cornerstone of therapy for treatment of advanced melanoma. Ne...
Analyzing county-level factors of oncology fellowship program development from 2015-2025.
9003 Background: In the United States (US), access to oncology care varies geographically. One factor that may contribute...
The association of baseline fatigue and severe cancer treatment toxicity by comorbid conditions: A pooled analysis.
11036 Background: Fatigue is commonly reported by patients with cancer. Patients who report fatigue are at greater risk of...
Lung cancer screening for early detection of suspicious lung nodules in Latin America (LUCAS-LATAM).
TPS10631 Background: Lung cancer (LC) remains the leading cause of cancer-related death in the Latin American (LATAM) regi...