Journal of Clinical Oncology
Articles in this Issue
Choose breath, not death: Improving lung cancer screening in the Christus Good Shepherd internal medicine resident clinic.
e23231 Background: Lung Cancer is by far the leading cause of cancer death, making up almost 25% of all cancer deaths. Shockingly, each year more people d...
Comprehensive profiling of cell-free DNAs to identify molecular characteristics related to advanced-stage triple-negative breast cancer in young women.
e13137 Background: Breast cancer in young women is more likely to present as the triple-negative (TNBC) subtype compared to older women. Understanding the...
Association of socioeconomic status with secondary primary malignancy risk and mortality.
e21559 Background: Patients with a melanoma history are at higher risk of developing a secondary primary malignancy (SPM), an independent and distinct can...
Real-world predictors of adverse clinical outcomes in pancreatic cancer using a machine-learning framework.
4186 Background: Completion of chemotherapy is crucial for clinical benefit and has been linked to improved outcomes, but is often challenging given the t...
Outcomes with nivolumab maintenance after autologous hematopoietic stem cell transplantation in relapsed/refractory Hodgkin lymphoma: A systematic review and meta-analysis.
e19037 Background: Hodgkin Lymphoma (HL) patients undergoing autologous stem cell transplantation (auto-SCT) remain at high risk for relapse, necessitatin...
Outcomes of prostate cancer patients hospitalized with viral respiratory illnesses: A national population-based study.
e17008 Background: Prostate cancer patients are exposed to hormonal anti-androgenic therapy as a part of their treatment regimen. Previous studies compare...
Results and recommendations for surveillance/follow-up of breast cancer undergoing adjuvant hormonotherapy.
e23179 Background: We conducted a 10-year retrospective review to design post-treatment monitoring plans for breast cancer patients receiving endocrine th...
Trodelvy use in advanced triple negative breast cancer in Australia (TRACIE): Study design and interim analysis.
e13130 Background: Sacituzumab govitecan (SG) is a novel option for advanced triple-negative breast cancer (TNBC), offering improvement in progression-fre...
A window of opportunity study for preoperative brigatinib in resectable anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC): WILDERNESS trial.
8040 Background: Although ALK inhibitors are approved for patients with ALK -positive recurrent and/or metastatic NSCLC or resecte...
Association of Claudin18.2 expression, PD-L1, and prognostic implications in gastric and gastroesophageal junction cancers.
e16094 Background: CLDN18.2-targeted therapies and immune checkpoint inhibitors (ICIs) are promising approaches for gastri...
Association of glucagon-like peptide 1 receptor agonists with cancer risk in obesity adults with and without diabetes: A target trial emulation study.
10508 Background: The use of glucagon-like peptide 1 receptor agonists (GLP-1RAs) has substantially expended given their remarkable benefits in managing o...
Codon 167 missense mutations in von Hippel-Lindau syndrome: Genotype-phenotype correlations in a population-based study.
10608 Background: Von Hippel-Lindau (VHL) disease is caused by germline mutations of the VHL gene, resulting in multicentric and m...
Fall risk assessment by QTUG device in geriatric cancer patients on chemotherapy at a tertiary care hospital.
1533 Background: Age-related changes, such as declines in muscle strength, balance, and coordination, are exacerbated by cancer and its treatments elevati...
Disparities in pediatric oncology outcomes in the occupied Palestinian territories: A retrospective study from Augusta Victoria Hospital.
1509 Background: Childhood cancer survival rates exceed 80% in high-income countries, but over 80% of the global burden occurs in low- and middle-income c...
Exploring prognostic nutritional index (PNI) and racial disparities in DLBCL.
e19047 Background: DLBCL is the most common subtype of non-Hodgkin lymphoma (NHL), with a projected incidence of 32,443 new cases per year by 2025. Recent...
Pilot study evaluating the addition of cemiplimab in BRAF-mutant anaplastic thyroid cancer after progression on dabrafenib and trametinib.
e18149 Background: Anaplastic thyroid cancer (ATC) is a rare but highly aggressive form of thyroid cancer. The FDA has approved the use of dabrafenib and...
Head and neck cancer mortality: Unequal progress and emerging disparities.
e13815 Background: Head and neck cancers (HNC) are often associated with significant morbidity due to their impact on essential functions such as speech,...
Incidence, predictors, and outcomes of venous thromboembolism in patients hospitalized with thyroid cancer: A nationwide analysis (2016–2021).
e18152 Background: Patients with thyroid cancer (TC), although at lower overall risk of venous thromboembolism (VTE) compared to other malignancies, are a...
Real-world treatment patterns in stage III ALK+ NSCLC patients in China: A multicenter retrospective study.
e20077 Background: Stage III non-small cell lung cancer (NSCLC) is highly heterogeneous and ALK+ patients (pts) lack of standard treatment model. Thus, th...
Detection of circulating tumor cells and PTEN loss in localized prostate cancer before and after radical prostatectomy: Prognostic implications and predictors of treatment response.
e17125 Background: There is a lack of reliable biomarkers to predict the recurrence of prostate cancer following prostatectomy, which can better guide sur...
Comparative effectiveness of first, second, and third-generation tyrosine kinase inhibitors in chronic myeloid leukemia: A systematic review and frequentist network meta-analysis.
e18564 Background: Tyrosine kinase inhibitors (TKIs) are highly effective for chronic myeloid leukemia (CML) carrying the BCR-ABL fusion gene. The advent...
Association of allostatic load (AL) and residential segregation with breast biopsy outcomes after screening mammography.
1620 Background: Allostatic Load (AL) and residential segregation have been associated with the risk of breast cancer (BC). However, the independent effec...
Exploring hidden risk: The prevalence of humoral immunodeficiency in patients with lymphoproliferative disorders—A prospective study.
e19083 Background: Infection is a significant cause of morbidity & mortality in patients with chronic lymphocytic leukemia (CLL), lymphoma, & mult...
The lost evidence: A phase III, multicenter randomized controlled trial of neoadjuvant chemotherapy paclitaxel plus cisplatin versus surgery alone for stage IIA–IIIB esophageal squamous cell carcinoma.
4074 Background: The efficacy of neoadjuvant chemotherapy (NAC) vs primary surgery alone for treatment of locally advanced esophageal squamous cell carcin...
Demographic and clinical factors associated with sleep disturbance in breast cancer survivors.
12083 Background: Fatigue and sleep disturbance are prevalent during and after cancer treatment; sleep-related symptoms affect 30-50% of patients with can...