Journal of Clinical Oncology
Articles in this Issue
Clinicopathologic features and prognostic factors of breast cancer brain metastases patients based on molecular subtypes: A real-world retrospective analysis.
e13077 Background: The incidence of breast cancer brain metastases (BCBM) is increasing. Molecular subtypes of breast canc...
Associations between mindfulness, psychological distress, and coping among hematopoietic stem cell transplant caregivers.
e18567 Background: Caregivers of allogeneic hematopoietic stem cell transplantation (HCT) patients experience significant...
Point-of-care cancer screening using saliva transmission spectroscopy and machine learning.
e22526 Background: Tier-1 cancer screening would benefit from point-of-care (POC) testing that is rapid, inexpensive, and...
Impact of social marginalization on stage at presentation and survival for invasive lobular versus ductal breast carcinoma.
641 Background: We aim to determine how indices of social marginalization impact stage at diagnosis, health services use,...
Natural language processing (NLP) to identify neoplastic fever in the electronic medical record (EMR).
e13679 Background: Neoplastic fever (also known as “tumor fever”; TF), is a rare but challenging condition that can be dif...
Symptom-based individual risk prediction for late mortality: A report from the Childhood Cancer Survivor Study study (CCSS).
10050 Background: Survivors of childhood cancer face a higher risk of late mortality than the general population. Yet no p...
Final results of a phase II study of fluorouracil (FU), leucovorin (LV), and nanoliposomal irinotecan (nal-IRI) in previously treated biliary tract cancer (NAPOLI-2).
4122 Background: BTCs are rare and aggressive malignancies. The first-line standard of care regimen for advanced BTC (aBTC...
Antibody-encapsulated actinomycin D for targeted cancer treatments.
e13019 Background: HER2 is overexpressed in 15-20% of breast cancers and other cancers, and HER2-targeted therapies have r...
Prevention of paclitaxel-induced neurotoxicity with lithium: Results from a multicenter, randomized, double-blind, placebo-controlled phase 2 trial (PREPARE).
12129 Background: Chemotherapy-induced neurotoxicity is a frequent adverse effect of paclitaxel (PTX). It reduces quality...
Prognostic value of an MRI-derived recurrence assay in women with hormone receptor–positive, HER2-negative breast cancer: A retrospective, multi-center analysis.
560 Background: Patients (pts) with early stage hormone receptor-positive, human epidermal growth factor receptor 2-negati...
Associations between chronic pain, depression, and social vulnerability in US adults with colon cancer.
e15698 Background: Chronic pain is a frequent and disabling sequela of colon cancer treatment, yet nationally representati...
Does resection of cavity shave margins impact survival in breast cancer patients?
513 Background: Randomized controlled trials have shown that resection of cavity shave margins (CSM) halves the margin pos...
Age-related immune toxicity and treatment outcomes in triple-negative breast cancer treated with pembrolizumab.
e12710 Background: Tolerability and treatment completion of pembrolizumab added to neoadjuvant chemotherapy for triple-neg...
Timing of central nervous system metastases occurrence in patients with metastatic breast cancer treated with CDK 4/6 inhibitors: A single institution real-world analysis.
e13068 Background: Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) are standard first-line treatment for patients with ho...
Real-world outcomes of bruton tyrosine kinase inhibitors versus venetoclax in chronic lymphocytic leukemia.
e18616 Background: Bruton tyrosine kinase inhibitors (BTKi) and venetoclax-based regimens have transformed the frontline m...
KANDLELIT-014: A phase 2 study of MK-1084 as monotherapy and in combination with cetuximab in <i>KRAS</i> G12C-mutant advanced solid tumors.
TPS3185 Background: KRAS is one of the most frequently mutated oncogenes in human cancers, with the G1...
Impact of first-line comprehensive genomic profiling on survival outcomes for patients with advanced solid tumors who received molecularly-matched therapies: 3-year follow-up of the prospective FIRST-Dx study.
3134 Background: Comprehensive genomic profiling (CGP) by next-generation sequencing has been reimbursed in Japan since 20...
Institutional disparities in actionable mutation detection in pancreatic ductal adenocarcinoma: An AACR Project GENIE analysis.
e16378 Background: The identification of actionable mutations in pancreatic ductal adenocarcinoma (PDAC) informs eligibili...
Response to neoadjuvant chemoimmunotherapy in EGFR- or ALK-mutated non-small cell lung cancer.
8054 Background: The role of immunotherapy in non-metastatic EGFR-and ALK-mutated lung cancer is limited, in part because...
Efficacy and safety of tislelizumab as neoadjuvant therapy combined with MRD monitoring in locally advanced dMMR/MSI-H colon cancer: A prospective pilot study.
3651 Background: PD-1 blockade has demonstrated high efficacy in metastatic and neoadjuvant settings for dMMR/MSI-H colore...
Factors contributing to non-initiation of planned systemic therapy among inpatients evaluated for a phase II randomized controlled oncology trial.
e23353 Background: The Spine Patient Optimal Radiosurgery Treatment for Symptomatic MEtastatic Neoplasms (SPORTSMEN) multi...
Retrospective evaluation of immune checkpoint inhibitors in soft tissue sarcoma.
e23570 Background: Soft tissue sarcomas (STS) are rare, and metastatic disease confers a poor prognosis. There are limited...
Cancer care experiences among sexual and gender minority adults: A qualitative descriptive study.
e13731 Background: Sexual and gender minority (SGM) individuals experience disparities across cancer screening, treatment,...
Patterns of artificial intelligence use among physicians in Mexico: Implications for oncology practice.
9002 Background: Artificial intelligence (AI) is increasingly incorporated into medical practice; however, physician-level...
Temporal trends in mortality involving esophageal cancer with comorbid psychoactive substance-induced mood disorders among adults aged ≥55 years in the United States, 1999–2023: A retrospective CDC WONDER analysis.
e16049 Background: Esophageal Cancer (EC) has strong association with mental and behavioral disorders caused by psychoacti...