Journal of Clinical Oncology
Articles in this Issue
Are patients with early-stage non-small cell lung cancer receiving timely testing for the ALK rearrangement?
e23276 Background: In the US, standard of care treatment for patients with ALK+ early-stage non-small cell lung cancer (eNSCLC) changed in April 2024, wit...
Inconsistent housing support for oncologic patients at NCI–Designated Cancer Centers.
e13520 Background: Affordable housing accommodations during cancer care is critical for reducing financial toxicity and improving patient outcomes....
Meta-analysis of CAR-T and bispecific antibodies in follicular lymphoma: A comparative efficacy assessment.
e19070 Background: Relapsed/refractory follicular lymphoma (RR-FL) presents significant treatment challenges due to its poor prognosis and limited effecti...
National trends in incidence of pancreatic cancer among adults aged 70 and older across 204 nations: A global burden of disease study (1990–2021).
e16421 Background: Worldwide, the incidence of pancreatic cancer (PC) is increasing. Assessing the burden of PC and its national patterns is critical for...
Adjuvant icotinib of 12 months versus observation as adjuvant therapy for completely resected EGFR-mutated stage IB non-small-cell lung cancer: 5-year update from CORIN (GASTO1003).
8021 Background: In the phase II CORIN trial,adjuvant therapy of icotinib for 1-year shows prolonged disease-free survival (DFS) and acceptable toxicity i...
Risk factors associated with de novo metastatic colorectal cancer in early onset colorectal cancer.
3529 Background: Early onset colorectal cancer (EO CRC) is rising worldwide. Epidemiologic studies have shown that diets high in sugar and/or processed fo...
Trends in the treatment of stage IIB/C and IIIA colorectal cancer: A National Cancer Database (NCDB) analysis.
e15658 Background: The standard treatment for early-stage colon cancer (CC) involves upfront surgical resection of the primary tumor and regional lymph no...
One size doesn’t FIT all: Early outcomes of implementing the ASCO PGA in an Australian public hospital.
e13850 Background: Older people present with impairments and pre-existing illnesses contributing to higher risks of cancer treatment complications, toxici...
Association of West African ancestry, reproductive factors, and deprivation with incidence of triple-negative breast cancer among Black women in the U.S.
1609 Background: Black women have the highest incidence of triple negative breast cancer (TNBC) of any racial or ethnic group in the U.S. The TNBC inciden...
Analytical validation and clinical performance of a plasma-based CGP assay, NEO | PanTracer LBx.
e15047 Background: Comprehensive genomic profiling (CGP) assays targeting hundreds of genes are increasingly used over smaller panels in patients with adv...
Predictive value of homologous recombination-related gene mutations in survival outcomes of first-line nivolumab plus chemotherapy for gastric cancer.
4048 Background: Homologous recombination repair (HRR) gene mutations are associated with genomic instability; however, their clinical value in the contex...
Extended endocrine therapy after 5 years of adjuvant LHRH-agonist in premenopausal patients with node-positive hormone receptor (HR)-positive early breast cancer.
537 Background: There is no evidence regarding the benefit of extended endocrine therapy (eET) beyond 5 years of adjuvant treatment with LHRH agonists (LH...
Aging and global cancer burden: A population-based comparative situation analysis and predictions from GLOBOCAN and UN databases.
e23253 Background: As the global population ages, the incidence and impact of cancer among the elderly have become critical areas of study. This demograph...
A patient advocacy-focused rehabilitation pilot program: Real-life experience in enhancing quality of life for metastatic lung cancer patients.
12079 Background: Living with lung cancer (LC) is a prolonged and challenging journey, where the disease's consequences and treatment-related adverse even...
Guard-01: A prospective study of efbemalenograstim alfa as primary prophylaxis for concurrent chemo-radiotherapy induced neutropenia.
e24100 Background: Concurrent chemo-radiotherapy (CCRT) holds a crucial role in the therapeutic regimen for diverse malignant tumors, yet it often leads t...
Treatment modalities and survival outcomes in patients with hepatocellular carcinoma with brain metastases (HCC-BM): A large national study.
e14007 Background: Hepatocellular carcinoma (HCC) with brain metastases (BM) is a rare and aggressive condition with poor survival outcomes and only a few...
A novel active chromatin cell-free DNA (cfDNAac) assay for early detection of colorectal cancer.
3605 Background: Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths globally (Xi et al. 2021)....
Understanding psychosocial wellbeing and concern for death and dying: Insights from a psycho-oncology clinic.
11105 Background: Patients with cancer face burden of mental health symptoms and an ongoing concern for death and dying. The psycho-oncology clinic aims t...
Co-mutational landscape of Indian core binding AML: An answer to the unfavorable outcome in a favorable AML?
6534 Background: Core binding factor AML, which encompasses RUNX1/RUNX1T1 and CBFB/MYH11, comprise 10-15% of all AML, currently classified as favorable ri...
Targeting preventable acute care events: A study on reducing emergency visits and hospitalizations in outpatient chemotherapy administrations.
e13584 Background: This study examined outpatient chemotherapy administrations that resulted in acute care events (ACE30) and preventable acute care event...
Demographic and clinical factors associated with care outcomes in hospitalized patients with cancer.
e23112 Background: Patients with cancer often require hospital-level care to address symptoms and side effects, yet a dearth of research has sought to ide...
Colorectal cancer mortality dynamics: Uncovering critical disparities in U.S. population health (2018–2023).
3583 Background: Colorectal cancer(CRC) remains the third leading cause of cancer-related deaths in the United States, with a disproportionate burden on u...
Mutation profiling of appendiceal cancer: Distinguishing tumor grades, comprehensive mutation landscape, and ctDNA as a discovery tool.
2564 Background: Appendiceal cancer (AC) encompasses rare tumors with varying clinical behavior. Histologic grade is a key determinant of disease biology...
Advancing therapeutic approaches for targeting KRAS in cancer treatment.
e16467 Background: PDAC is challenging to treat due to its dense stroma with 50% of cases driven by KRASG12D mutations. Recently discovered KRAS12D inhibi...
A novel machine learning approach to breast cancer screening using non-invasive mRNA collection.
e13609 Background: Current breast cancer diagnostic methods are often highly-invasive or painful, deterring many from screening. While DNA-based methods s...